Biobanks as an important tool in modern translational oncology

Translational Polymorphism as an Important Source of Eukaryotic Proteins Variety

Translation of most eukaryotic mRNAs is likely to be initiated by a linear scanning mechanism, although some other mechanisms are also possible [1]. According to the scanning model, 40S ribosomal subunits can either initiate translation at 5’-proximal AUG codon in a suboptimal context or miss it and initiate translation at downstream AUG(s) [1]. Eukaryotic mRNAs are often characterized by a sub...

Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research

The Thoracic Oncology Program Database Project was created to serve as a comprehensive, verified, and accessible repository for well-annotated cancer specimens and clinical data to be available to researchers within the Thoracic Oncology Research Program. This database also captures a large volume of genomic and proteomic data obtained from various tumor tissue studies. A team of clinical and b...

Immunocap ISAC as an important diagnostic tool in rhino-sinusitis

Results The patient (smoker) complained on a variety of symptoms that were bothering her for more than 3 years: headaches, significant fatigue, nasal blockage, breathlessness on exercise and occasionally at rest. There were no ocular symptoms. She had several courses of antibiotics during this period with slight improvement. Careful history revealed progressive deterioration in her condition; t...

Tourism as an Economic Develpment Tool

Fire as an engineering tool of early modern humans.

The controlled use of fire was a breakthrough adaptation in human evolution. It first provided heat and light and later allowed the physical properties of materials to be manipulated for the production of ceramics and metals. The analysis of tools at multiple sites shows that the source stone materials were systematically manipulated with fire to improve their flaking properties. Heat treatment...